IFI27/ISG12 Downregulates Estrogen Receptor α Transactivation by Facilitating Its Interaction With CRM1/XPO1 in Breast Cancer Cells

The estrogen receptor alpha (ERα) is a ligand-activated transcription factor whose activity is modulated by its interaction with multiple protein complexes. In this work, we have identified the protein interferon alpha inducible protein 27 (IFI27/ISG12) as a novel ERα-associated protein. IFI27/ISG12...

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Publicado no:Front Endocrinol (Lausanne)
Main Authors: Cervantes-Badillo, Mayte Guadalupe, Paredes-Villa, Alejandro, Gómez-Romero, Vania, Cervantes-Roldán, Rafael, Arias-Romero, Luis E., Villamar-Cruz, Olga, González-Montiel, Miroslava, Barrios-García, Tonatiuh, Cabrera-Quintero, Alberto J., Rodríguez-Gómez, Gabriel, Cancino-Villeda, Laura, Zentella-Dehesa, Alejandro, León-Del-Río, Alfonso
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7575815/
https://ncbi.nlm.nih.gov/pubmed/33117284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2020.568375
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