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CRM1/XPO1 expression in pancreatic adenocarcinoma correlates with survivin expression and the proliferative activity
CRM1/XPO1 (CRM1) is a nuclear export chaperone that mediates the export of proteins essential to growth regulation and tumor suppression. Its overexpression in tumors was found to be associated with poor prognosis. Selective inhibitors of nuclear export are in phase I and II clinical trials for seve...
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| Опубликовано в: : | Oncotarget |
|---|---|
| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Impact Journals LLC
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5940369/ https://ncbi.nlm.nih.gov/pubmed/29765539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25088 |
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