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The past, present, and future of CRM1/XPO1 inhibitors

Therapies targeted at inhibiting nucleo-cytoplasmic transport have found broad applications in the field of oncology. Chromosome region maintenance 1 (CRM1), better known as exportin 1 (XPO1), is the protein transporter responsible for the nucleo-cytoplasmic shuttling of most of the tumor suppressor...

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Detalhes bibliográficos
Publicado no:Stem Cell Investig
Main Authors: Wang, Amy Y., Liu, Hongtao
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6414360/
https://ncbi.nlm.nih.gov/pubmed/30976603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/sci.2019.02.03
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