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CRM1/XPO1 expression in pancreatic adenocarcinoma correlates with survivin expression and the proliferative activity

CRM1/XPO1 (CRM1) is a nuclear export chaperone that mediates the export of proteins essential to growth regulation and tumor suppression. Its overexpression in tumors was found to be associated with poor prognosis. Selective inhibitors of nuclear export are in phase I and II clinical trials for seve...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Saulino, David M., Younes, Pamela S., Bailey, Jennifer M., Younes, Mamoun
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940369/
https://ncbi.nlm.nih.gov/pubmed/29765539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25088
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