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Comparisons of screening strategies for identifying Lynch syndrome among patients with MLH1-deficient colorectal cancer

BRAF and MLH1 promoter methylation testings have been proven effective prescreens for Lynch Syndrome. We aimed to compare different screening strategies for Lynch Syndrome in patients with MLH1(−) CRC. Patients with MLH1(−) CRC who had been tested for BRAF mutation and germline variants of DNA misma...

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Detalles Bibliográficos
Publicado en:Eur J Hum Genet
Main Authors: Xiao, Binyi, Luo, Jun, Xie, E., Kong, Lingheng, Tang, Jinghua, Liu, Dingxin, Mao, Linlin, Sui, Qiaoqi, Li, Weirong, Hong, Zhigang, Pan, Zhizhong, Jiang, Wu, Ding, Pei-Rong
Formato: Artigo
Idioma:Inglês
Publicado: Springer International Publishing 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7575538/
https://ncbi.nlm.nih.gov/pubmed/32661327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41431-020-0687-8
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