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A frameshift mutation in exon 19 of MLH1 in a Chinese Lynch syndrome family: a pedigree study

lynch syndrome (LS), an autosomal dominantly inherited disease previously known as hereditary non-polyposis colorectal cancer (HNPCC), leads to a high risk of colorectal cancer (CRC) as well as malignancy at certain sites including endometrium, ovary, stomach, and small bowel (Hampel et al., 2008; L...

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Detalhes bibliográficos
Publicado no:J Zhejiang Univ Sci B
Main Authors: Sui, Qiao-qi, Jiang, Wu, Wu, Xiao-dan, Ling, Yi-hong, Pan, Zhi-zhong, Ding, Pei-rong
Formato: Artigo
Idioma:Inglês
Publicado em: Zhejiang University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6331328/
https://ncbi.nlm.nih.gov/pubmed/30614234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1631/jzus.B1800105
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