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A Chinese family affected by lynch syndrome caused by MLH1 mutation
BACKGROUND: Lynch syndrome (LS) is caused by mutations in DNA mismatch repair (MMR) genes, which accounts for 3–5% of colorectal cancer. The risks of several types of cancer are greatly increased among individuals with LS. In this study, 4 members of a Chinese family with a MLH1 pathogenic variant,...
Gorde:
| Argitaratua izan da: | BMC Med Genet |
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| Egile Nagusiak: | , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
BioMed Central
2018
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6014015/ https://ncbi.nlm.nih.gov/pubmed/29929473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-018-0605-x |
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