Neural stem cells derived from the developing forebrain of YAC128 mice exhibit pathological features of Huntington’s disease

OBJECTIVES: Huntington's disease (HD) is a devastating neurodegenerative disease caused by polyglutamine (polyQ) expansion in the huntingtin (HTT) gene. Mutant huntingtin (mHTT) is the main cause of HD and is associated with impaired mitochondrial dynamics, ubiquitin‐proteasome system and autop...

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Dettagli Bibliografici
Pubblicato in:Cell Prolif
Autori principali: Li, Endan, Park, Hee Ra, Hong, Chang Pyo, Kim, Younghoon, Choi, Jiwoo, Lee, Suji, Park, Hyun Jung, Lee, Bomi, Kim, Tae Aug, Kim, Seong Jin, Kim, Hyun Sook, Song, Jihwan
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7574873/
https://ncbi.nlm.nih.gov/pubmed/32865873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12893
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