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Transplantation of patient-derived adipose stem cells in YAC128 Huntington's disease transgenic mice

Huntington’s disease (HD) is a genetic neurodegenerative disorder caused by abnormal expansion of CAG in the huntingtin gene. In R6/2 HD transgenic mice, human adipose-derived stem cells (ASCs) can slow disease progression via secretion of multiple paracrine growth factors. In order to prompt autolo...

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Bibliografische gegevens
Hoofdauteurs: Im, Wooseok, Lee, Soon-Tae, Park, Jeong Eun, Oh, hyun Jung, Shim, Jiyoung, Lim, Jiyeon, Chu, Kon, Kim, Manho
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946829/
https://ncbi.nlm.nih.gov/pubmed/20890444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/currents.RRN1183
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