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Neural stem cells derived from the developing forebrain of YAC128 mice exhibit pathological features of Huntington’s disease

OBJECTIVES: Huntington's disease (HD) is a devastating neurodegenerative disease caused by polyglutamine (polyQ) expansion in the huntingtin (HTT) gene. Mutant huntingtin (mHTT) is the main cause of HD and is associated with impaired mitochondrial dynamics, ubiquitin‐proteasome system and autop...

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Detalhes bibliográficos
Publicado no:Cell Prolif
Main Authors: Li, Endan, Park, Hee Ra, Hong, Chang Pyo, Kim, Younghoon, Choi, Jiwoo, Lee, Suji, Park, Hyun Jung, Lee, Bomi, Kim, Tae Aug, Kim, Seong Jin, Kim, Hyun Sook, Song, Jihwan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7574873/
https://ncbi.nlm.nih.gov/pubmed/32865873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12893
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