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Cofactor Binding Dynamics Influence the Catalytic Activity and Selectivity of an Artificial Metalloenzyme
[Image: see text] We present an artificial metalloenzyme based on the transcriptional regulator LmrR that exhibits dynamics involving the positioning of its abiological metal cofactor. The position of the cofactor, in turn, was found to be related to the preferred catalytic reactivity, which is eith...
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| Pubblicato in: | ACS Catal |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Chemical Society
2020
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7574625/ https://ncbi.nlm.nih.gov/pubmed/33101759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.0c01619 |
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