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In Vivo Assembly of Artificial Metalloenzymes and Application in Whole‐Cell Biocatalysis

We report the supramolecular assembly of artificial metalloenzymes (ArMs), based on the Lactococcal multidrug resistance regulator (LmrR) and an exogeneous copper(II)–phenanthroline complex, in the cytoplasm of E. coli cells. A combination of catalysis, cell‐fractionation, and inhibitor experiments,...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Chordia, Shreyans, Narasimhan, Siddarth, Lucini Paioni, Alessandra, Baldus, Marc, Roelfes, Gerard
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986609/
https://ncbi.nlm.nih.gov/pubmed/33428816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202014771
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