A Hydroxyquinoline‐Based Unnatural Amino Acid for the Design of Novel Artificial Metalloenzymes

We have examined the potential of the noncanonical amino acid (8‐hydroxyquinolin‐3‐yl)alanine (HQAla) for the design of artificial metalloenzymes. HQAla, a versatile chelator of late transition metals, was introduced into the lactococcal multidrug‐resistance regulator (LmrR) by stop codon suppressio...

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Bibliografische gegevens
Gepubliceerd in:Chembiochem
Hoofdauteurs: Drienovská, Ivana, Scheele, Remkes A., Gutiérrez de Souza, Cora, Roelfes, Gerard
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2020
Onderwerpen:
Communications
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7689906/
https://ncbi.nlm.nih.gov/pubmed/32585070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.202000306
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