An Artificial Heme Enzyme for Cyclopropanation Reactions

An artificial heme enzyme was created through self‐assembly from hemin and the lactococcal multidrug resistance regulator (LmrR). The crystal structure shows the heme bound inside the hydrophobic pore of the protein, where it appears inaccessible for substrates. However, good catalytic activity and...

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Bibliografski detalji
Izdano u:Angew Chem Int Ed Engl
Glavni autori: Villarino, Lara, Splan, Kathryn E., Reddem, Eswar, Alonso‐Cotchico, Lur, Gutiérrez de Souza, Cora, Lledós, Agustí, Maréchal, Jean‐Didier, Thunnissen, Andy‐Mark W. H., Roelfes, Gerard
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Communications
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033091/
https://ncbi.nlm.nih.gov/pubmed/29719099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201802946
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