Live-cell super-resolved PAINT imaging of pN cellular traction forces

Despite the vital role of mechanical forces in biology, no technique has been reported to image cellular force with sub-100 nm resolution. Here, we present tension-PAINT (tPAINT), integrating molecular tension probes with the DNA-PAINT technique to map pN mechanical events with ~25 nm resolution. To...

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Detaylı Bibliyografya
Yayımlandı:Nat Methods
Asıl Yazarlar: Brockman, Joshua M., Su, Hanquan, Blanchard, Aaron T., Duan, Yuxin, Meyer, Travis, Quach, M. Edward, Glazier, Roxanne, Bazrafshan, Alisina, Bender, Rachel L., Kellner, Anna V., Ogasawara, Hiroaki, Ma, Rong, Schueder, Florian, Petrich, Brian G., Jungmann, Ralf, Li, Renhao, Mattheyses, Alexa L., Ke, Yonggang, Salaita, Khalid
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7574592/
https://ncbi.nlm.nih.gov/pubmed/32929270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-020-0929-2
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