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The pVHL neglected functions, a tale of hypoxia-dependent and -independent regulations in cancer
The von Hippel–Lindau protein (pVHL) is a tumour suppressor mainly known for its role as master regulator of hypoxia-inducible factor (HIF) activity. Functional inactivation of pVHL is causative of the von Hippel–Lindau disease, an inherited predisposition to develop different cancers. Due to its im...
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| Veröffentlicht in: | Open Biol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Royal Society
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7574549/ https://ncbi.nlm.nih.gov/pubmed/32603638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.200109 |
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