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Cancer prognosis prediction using somatic point mutation and copy number variation data: a comparison of gene-level and pathway-based models

BACKGROUND: Genomic profiling of solid human tumors by projects such as The Cancer Genome Atlas (TCGA) has provided important information regarding the somatic alterations that drive cancer progression and patient survival. Although researchers have successfully leveraged TCGA data to build prognost...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Zheng, Xingyu, Amos, Christopher I., Frost, H. Robert
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7574407/
https://ncbi.nlm.nih.gov/pubmed/33081688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03791-0
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