Somatic mutations and copy number variations in breast cancers with heterogeneous HER2 amplification

Intratumour heterogeneity fuels carcinogenesis and allows circumventing specific targeted therapies. HER2 gene amplification is associated with poor outcome in invasive breast cancer. Heterogeneous HER2 amplification has been described in 5–41% of breast cancers. Here, we investigated the genetic di...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Van Bockstal, Mieke R., Agahozo, Marie Colombe, van Marion, Ronald, Atmodimedjo, Peggy N., Sleddens, Hein F. B. M., Dinjens, Winand N. M., Visser, Lindy L., Lips, Esther H., Wesseling, Jelle, van Deurzen, Carolien H. M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7138394/
https://ncbi.nlm.nih.gov/pubmed/32058674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12650
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