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Somatic mutations and copy number variations in breast cancers with heterogeneous HER2 amplification

Intratumour heterogeneity fuels carcinogenesis and allows circumventing specific targeted therapies. HER2 gene amplification is associated with poor outcome in invasive breast cancer. Heterogeneous HER2 amplification has been described in 5–41% of breast cancers. Here, we investigated the genetic di...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Oncol
मुख्य लेखकों: Van Bockstal, Mieke R., Agahozo, Marie Colombe, van Marion, Ronald, Atmodimedjo, Peggy N., Sleddens, Hein F. B. M., Dinjens, Winand N. M., Visser, Lindy L., Lips, Esther H., Wesseling, Jelle, van Deurzen, Carolien H. M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: John Wiley and Sons Inc. 2020
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7138394/
https://ncbi.nlm.nih.gov/pubmed/32058674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12650
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