Prognostic relevance of mutations and copy number alterations assessed with targeted next generation sequencing in IDH mutant grade II glioma

BACKGROUND: At current prognostication of low grade glioma remains suboptimal and might be improved with additional markers. These may guide treatment decisions, in particular on early adjuvant therapy versus wait and see after surgery. METHODS: We used a targeted Next-Generation Sequencing panel to...

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Bibliografski detalji
Izdano u:J Neurooncol
Glavni autori: Wijnenga, Maarten M. J., French, Pim J., Dubbink, Hendrikus J., Dinjens, Winand N. M., Atmodimedjo, Peggy N., Kros, Johan M., Fleischeuer, Ruth, Dirven, Clemens M. F., Vincent, Arnaud J. P. E., van den Bent, Martin J.
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2018
Teme:
Clinical Study
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096891/
https://ncbi.nlm.nih.gov/pubmed/29663171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-018-2867-8
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