Prognostic relevance of mutations and copy number alterations assessed with targeted next generation sequencing in IDH mutant grade II glioma

BACKGROUND: At current prognostication of low grade glioma remains suboptimal and might be improved with additional markers. These may guide treatment decisions, in particular on early adjuvant therapy versus wait and see after surgery. METHODS: We used a targeted Next-Generation Sequencing panel to...

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Detalhes bibliográficos
Publicado no:J Neurooncol
Main Authors: Wijnenga, Maarten M. J., French, Pim J., Dubbink, Hendrikus J., Dinjens, Winand N. M., Atmodimedjo, Peggy N., Kros, Johan M., Fleischeuer, Ruth, Dirven, Clemens M. F., Vincent, Arnaud J. P. E., van den Bent, Martin J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2018
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096891/
https://ncbi.nlm.nih.gov/pubmed/29663171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-018-2867-8
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