Prognostic relevance of mutations and copy number alterations assessed with targeted next generation sequencing in IDH mutant grade II glioma

BACKGROUND: At current prognostication of low grade glioma remains suboptimal and might be improved with additional markers. These may guide treatment decisions, in particular on early adjuvant therapy versus wait and see after surgery. METHODS: We used a targeted Next-Generation Sequencing panel to...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Neurooncol
Auteurs principaux: Wijnenga, Maarten M. J., French, Pim J., Dubbink, Hendrikus J., Dinjens, Winand N. M., Atmodimedjo, Peggy N., Kros, Johan M., Fleischeuer, Ruth, Dirven, Clemens M. F., Vincent, Arnaud J. P. E., van den Bent, Martin J.
Format: Artigo
Langue:Inglês
Publié: Springer US 2018
Sujets:
Clinical Study
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096891/
https://ncbi.nlm.nih.gov/pubmed/29663171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-018-2867-8
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