Prognostic relevance of mutations and copy number alterations assessed with targeted next generation sequencing in IDH mutant grade II glioma

BACKGROUND: At current prognostication of low grade glioma remains suboptimal and might be improved with additional markers. These may guide treatment decisions, in particular on early adjuvant therapy versus wait and see after surgery. METHODS: We used a targeted Next-Generation Sequencing panel to...

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Bibliografiske detaljer
Udgivet i:J Neurooncol
Main Authors: Wijnenga, Maarten M. J., French, Pim J., Dubbink, Hendrikus J., Dinjens, Winand N. M., Atmodimedjo, Peggy N., Kros, Johan M., Fleischeuer, Ruth, Dirven, Clemens M. F., Vincent, Arnaud J. P. E., van den Bent, Martin J.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2018
Fag:
Clinical Study
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096891/
https://ncbi.nlm.nih.gov/pubmed/29663171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-018-2867-8
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