טוען...
DNA hydroxymethylation increases the susceptibility of reactivation of methylated P16 alleles in cancer cells
It is well established that 5-methylcytosine (5mC) in genomic DNA of mammalian cells can be oxidized into 5-hydroxymethylcytosine (5hmC) and other derivates by DNA dioxygenase TETs. While conversion of 5mC to 5hmC plays an important role in active DNA demethylation through further oxidation steps, a...
שמור ב:
| הוצא לאור ב: | Epigenetics |
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| Main Authors: | , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Taylor & Francis
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7574387/ https://ncbi.nlm.nih.gov/pubmed/31790633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2019.1700004 |
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