Two novel SIRT1 activators, SCIC2 and SCIC2.1, enhance SIRT1-mediated effects in stress response and senescence

SIRT1, a NAD(+)-dependent deacetylase, is the most well-studied member of class III histone deacetylases. Due to its wide range of activities and substrate targets, this enzyme has emerged as a major regulator of different physiological processes. However, SIRT1-mediated alterations are also implica...

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Enregistré dans:
Détails bibliographiques
Publié dans:Epigenetics
Auteurs principaux: Scisciola, Lucia, Sarno, Federica, Carafa, Vincenzo, Cosconati, Sandro, Di Maro, Salvatore, Ciuffreda, Loreta, De Angelis, Antonella, Stiuso, Paola, Feoli, Alessandra, Sbardella, Gianluca, Altucci, Lucia, Nebbioso, Angela
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2020
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7574383/
https://ncbi.nlm.nih.gov/pubmed/31942817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2019.1704349
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