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Single Amino Acid Replacements in RocA Disrupt Protein-Protein Interactions To Alter the Molecular Pathogenesis of Group A Streptococcus

Group A Streptococcus (GAS) is a human-specific pathogen and major cause of disease worldwide. The molecular pathogenesis of GAS, like many pathogens, is dependent on the coordinated expression of genes encoding different virulence factors. The control of virulence regulator/sensor (CovRS) two-compo...

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Bibliografische gegevens
Gepubliceerd in:Infect Immun
Hoofdauteurs: Bernard, Paul E., Duarte, Amey, Bogdanov, Mikhail, Musser, James M., Olsen, Randall J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7573446/
https://ncbi.nlm.nih.gov/pubmed/32817331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00386-20
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