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Intergenic Variable-Number Tandem-Repeat Polymorphism Upstream of rocA Alters Toxin Production and Enhances Virulence in Streptococcus pyogenes

Variable-number tandem-repeat (VNTR) polymorphisms are ubiquitous in bacteria. However, only a small fraction of them has been functionally studied. Here, we report an intergenic VNTR polymorphism that confers an altered level of toxin production and increased virulence in Streptococcus pyogenes. Th...

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Detalles Bibliográficos
Publicado en:Infect Immun
Main Authors: Zhu, Luchang, Olsen, Randall J., Horstmann, Nicola, Shelburne, Samuel A., Fan, Jia, Hu, Ye, Musser, James M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936349/
https://ncbi.nlm.nih.gov/pubmed/27141081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00258-16
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