Opacification Domain of Serum Opacity Factor Inhibits Beta-Hemolysis and Contributes to Virulence of Streptococcus pyogenes

Serum opacity factor (SOF) is a cell surface virulence factor made by the human pathogen Streptococcus pyogenes. We found that S. pyogenes strains with naturally occurring truncation mutations in the sof gene have markedly enhanced beta-hemolysis. Moreover, deletion of the sof gene in a SOF-positive...

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Bibliographic Details
Published in:mSphere
Main Authors: Zhu, Luchang, Olsen, Randall J., Musser, James M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397570/
https://ncbi.nlm.nih.gov/pubmed/28435893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphereDirect.00147-17
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