Single Amino Acid Replacements in RocA Disrupt Protein-Protein Interactions To Alter the Molecular Pathogenesis of Group A Streptococcus

Group A Streptococcus (GAS) is a human-specific pathogen and major cause of disease worldwide. The molecular pathogenesis of GAS, like many pathogens, is dependent on the coordinated expression of genes encoding different virulence factors. The control of virulence regulator/sensor (CovRS) two-compo...

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Vydáno v:Infect Immun
Hlavní autoři: Bernard, Paul E., Duarte, Amey, Bogdanov, Mikhail, Musser, James M., Olsen, Randall J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
Témata:
Molecular Pathogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7573446/
https://ncbi.nlm.nih.gov/pubmed/32817331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00386-20
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