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Distinct Single Amino Acid Replacements in the Control of Virulence Regulator Protein Differentially Impact Streptococcal Pathogenesis

Sequencing of invasive strains of group A streptococci (GAS) has revealed a diverse array of single nucleotide polymorphisms in the gene encoding the control of virulence regulator (CovR) protein. However, there is limited information regarding the molecular mechanisms by which CovR single amino aci...

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Библиографические подробности
Главные авторы: Horstmann, Nicola, Sahasrabhojane, Pranoti, Suber, Bryce, Kumaraswami, Muthiah, Olsen, Randall J., Flores, Anthony, Musser, James M., Brennan, Richard G., Shelburne, Samuel A.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197619/
https://ncbi.nlm.nih.gov/pubmed/22028655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002311
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