Distinct Single Amino Acid Replacements in the Control of Virulence Regulator Protein Differentially Impact Streptococcal Pathogenesis

Sequencing of invasive strains of group A streptococci (GAS) has revealed a diverse array of single nucleotide polymorphisms in the gene encoding the control of virulence regulator (CovR) protein. However, there is limited information regarding the molecular mechanisms by which CovR single amino aci...

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Main Authors: Horstmann, Nicola, Sahasrabhojane, Pranoti, Suber, Bryce, Kumaraswami, Muthiah, Olsen, Randall J., Flores, Anthony, Musser, James M., Brennan, Richard G., Shelburne, Samuel A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197619/
https://ncbi.nlm.nih.gov/pubmed/22028655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002311
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