Distinct Single Amino Acid Replacements in the Control of Virulence Regulator Protein Differentially Impact Streptococcal Pathogenesis

Sequencing of invasive strains of group A streptococci (GAS) has revealed a diverse array of single nucleotide polymorphisms in the gene encoding the control of virulence regulator (CovR) protein. However, there is limited information regarding the molecular mechanisms by which CovR single amino aci...

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Autors principals: Horstmann, Nicola, Sahasrabhojane, Pranoti, Suber, Bryce, Kumaraswami, Muthiah, Olsen, Randall J., Flores, Anthony, Musser, James M., Brennan, Richard G., Shelburne, Samuel A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197619/
https://ncbi.nlm.nih.gov/pubmed/22028655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002311
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