Monitoring Allosteric Interactions with CXCR4 Using NanoBiT Conjugated Nanobodies

Camelid single-domain antibody fragments (nanobodies) offer the specificity of an antibody in a single 15-kDa immunoglobulin domain. Their small size allows for easy genetic manipulation of the nanobody sequence to incorporate protein tags, facilitating their use as biochemical probes. The nanobody...

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Publicado en:Cell Chem Biol
Autores principales: Soave, Mark, Heukers, Raimond, Kellam, Barrie, Woolard, Jeanette, Smit, Martine J., Briddon, Stephen J., Hill, Stephen J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cell Press 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7573392/
https://ncbi.nlm.nih.gov/pubmed/32610042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2020.06.006
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