The BBSome assembly is spatially controlled by BBS1 and BBS4 in human cells

Bardet–Biedl syndrome (BBS) is a pleiotropic ciliopathy caused by dysfunction of primary cilia. More than half of BBS patients carry mutations in one of eight genes encoding for subunits of a protein complex, the BBSome, which mediates trafficking of ciliary cargoes. In this study, we elucidated the...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Prasai, Avishek, Schmidt Cernohorska, Marketa, Ruppova, Klara, Niederlova, Veronika, Andelova, Monika, Draber, Peter, Stepanek, Ondrej, Huranova, Martina
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2020
Teme:
Cell Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7573277/
https://ncbi.nlm.nih.gov/pubmed/32759308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013905
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