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BBS4 and BBS5 show functional redundancy in the BBSome to regulate the degradative sorting of ciliary sensory receptors

Cilia harbor sensory receptors for various signaling cascades critical for vertebrate development. However, the mechanisms underlying the ciliary homeostasis of sensory receptors remain elusive. Here, we demonstrate that BBS-4 and BBS-5, two distinct BBSome components, show unexpected functional red...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Xu, Qingwen, Zhang, Yuxia, Wei, Qing, Huang, Yan, Li, Yan, Ling, Kun, Hu, Jinghua
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493597/
https://ncbi.nlm.nih.gov/pubmed/26150102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11855
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