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The Centriolar Satellite Protein AZI1 Interacts with BBS4 and Regulates Ciliary Trafficking of the BBSome

Bardet-Biedl syndrome (BBS) is a well-known ciliopathy with mutations reported in 18 different genes. Most of the protein products of the BBS genes localize at or near the primary cilium and the centrosome. Near the centrosome, BBS proteins interact with centriolar satellite proteins, and the BBSome...

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Autors principals: Chamling, Xitiz, Seo, Seongjin, Searby, Charles C., Kim, GunHee, Slusarski, Diane C., Sheffield, Val C.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923683/
https://ncbi.nlm.nih.gov/pubmed/24550735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004083
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