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BBS4 and BBS5 show functional redundancy in the BBSome to regulate the degradative sorting of ciliary sensory receptors

Cilia harbor sensory receptors for various signaling cascades critical for vertebrate development. However, the mechanisms underlying the ciliary homeostasis of sensory receptors remain elusive. Here, we demonstrate that BBS-4 and BBS-5, two distinct BBSome components, show unexpected functional red...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Xu, Qingwen, Zhang, Yuxia, Wei, Qing, Huang, Yan, Li, Yan, Ling, Kun, Hu, Jinghua
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493597/
https://ncbi.nlm.nih.gov/pubmed/26150102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11855
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