BBSome Component BBS5 Is Required for Cone Photoreceptor Protein Trafficking and Outer Segment Maintenance

PURPOSE: To identify the role of the BBSome protein Bardet–Biedl syndrome 5 (BBS5) in photoreceptor function, protein trafficking, and structure using a congenital mutant mouse model. METHODS: Bbs5(–)(/)(–) mice (2 and 9 months old) were used to assess retinal function and morphology. Hematoxylin an...

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Vydáno v:Invest Ophthalmol Vis Sci
Hlavní autoři: Bales, Katie L., Bentley, Melissa R., Croyle, Mandy J., Kesterson, Robert A., Yoder, Bradley K., Gross, Alecia K.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Association for Research in Vision and Ophthalmology 2020
Témata:
Retinal Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7441369/
https://ncbi.nlm.nih.gov/pubmed/32776140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.10.17
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