27-Hydroxycholesterol acts on myeloid immune cells to induce T cell dysfunction, promoting breast cancer progression.

Breast cancer remains one of the leading causes of cancer mortality in the US. Elevated cholesterol is a major risk factor for breast cancer onset and recurrence, while cholesterol-lowering drugs, such as statins, are associated with a good prognosis. Previous work in murine models showed that chole...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Cancer Lett
Main Authors: Ma, Liqian, Wang, Lawrence, Nelson, Adam T., Han, Chaeyeon, He, Sisi, Henn, Madeline A., Menon, Karan, Chen, Joy J., Baek, Amy E., Vardanyan, Anna, Shahoei, Sayyed Hamed, Park, Sunghee, Shapiro, David J., Nanjappa, Som G., Nelson, Erik R.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7572761/
https://ncbi.nlm.nih.gov/pubmed/32861706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2020.08.020
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki