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Host CYP27A1 expression is essential for ovarian cancer progression.

There is an urgent need for more effective strategies to treat ovarian cancer. Elevated cholesterol levels are associated with a decreased progression free survival time (PFS) while statins are protective. 27-hydroxycholesterol (27HC), a primary metabolite of cholesterol has been shown to modulate t...

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Detalhes bibliográficos
Publicado no:Endocr Relat Cancer
Main Authors: He, Sisi, Ma, Liqian, Baek, Amy E., Vardanyan, Anna, Vembar, Varsha, Chen, Joy J., Nelson, Adam T., Burdette, Joanna E., Nelson, Erik R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824983/
https://ncbi.nlm.nih.gov/pubmed/31048561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-18-0572
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