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Decreased expression of CYP27B1 correlates with the increased aggressiveness of ovarian carcinomas

CYP27B1 hydroxylates 25-hydroxyvitamin D(3) in position C1α into biologically active 1,25-dihydroxyvitamin D(3), calcitriol. CYP27B1 is expressed in normal tissues and tumors. Since calcitriol indicates anticancer activities and CYP27B1 expression can be deregulated during malignant progression, we...

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Detalhes bibliográficos
Publicado no:Oncol Rep
Main Authors: BROŻYNA, ANNA A., JÓŹWICKI, WOJCIECH, JOCHYMSKI, CEZARY, SLOMINSKI, ANDRZEJ T.
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306272/
https://ncbi.nlm.nih.gov/pubmed/25501638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2014.3666
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