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Expression of Vitamin D-Activating Enzyme 1α-Hydroxylase (CYP27B1) Decreases during Melanoma Progression

1α-Hydroxylase (CYP27B1), the enzyme responsible for the synthesis of the biologically active form of vitamin D (1,25(OH)(2)D(3)), is expressed in the skin. To assess the correlation between progression of melanocytic tumors and CYP27B1, we analyzed its expression in 29 benign nevi, 75 primary cutan...

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Huvudupphovsmän: Brożyna, Anna A., Jóźwicki, Wojciech, Janjetovic, Zorica, Slominski, Andrzej T.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529817/
https://ncbi.nlm.nih.gov/pubmed/22995334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humpath.2012.03.031
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