Cargando...

Critical Residue Properties for Potency and Selectivity of α-Conotoxin RgIA Towards α9α10 Nicotinic Acetylcholine Receptors

The α9α10 nicotinic acetylcholine receptor (nAChR) has been characterized as an effective anti-pain target that functions through a non-opioid mechanism. However, as a pentameric ion channel comprised of two different subunits, the specific targeting of α9α10 nAChRs has proven challenging. Previousl...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Biochem Pharmacol
Main Authors: Huynh, Peter N., Harvey, Peta J., Gajewiak, Joanna, Craik, David J., Michael McIntosh, J.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7572646/
https://ncbi.nlm.nih.gov/pubmed/32593612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2020.114124
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!