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The α9α10 nicotinic acetylcholine receptors antagonist α-conotoxin RgIA reverses colitis signs in Murine Dextran Sodium Sulfate Model

Nicotinic acetylcholine receptors can regulate inflammation primarily through the vagus nerve via the cholinergic anti-inflammatory pathway. α9α10 nicotinic receptors (nAChRs) are a new promising target for chronic pain and inflammation. Recently, α9α10 selective α-conotoxin antagonists were shown t...

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Detalhes bibliográficos
Publicado no:Eur J Pharmacol
Main Authors: AlSharari, Shakir D, Toma, Wisam, Mahmood, Hafiz M., McIntosh, J. Michael, Damaj, M. Imad
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484279/
https://ncbi.nlm.nih.gov/pubmed/32645334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2020.173320
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