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In vivo molecular signatures of cerebellar pathology in spinocerebellar ataxia type 3

BACKGROUND: No treatment exists for the most common dominantly inherited ataxia Machado-Joseph disease, or spinocerebellar ataxia type 3 (SCA3). Successful evaluation of candidate therapeutics will be facilitated by validated noninvasive biomarkers of disease pathology recapitulated by animal models...

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Publicat a:Mov Disord
Autors principals: Costa, Maria do Carmo, Radzwion, Maria, McLoughlin, Hayley S., Ashraf, Naila S., Fischer, Svetlana, Shakkottai, Vikram G., Maciel, Patrícia, Paulson, Henry L., Öz, Gülin
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7572607/
https://ncbi.nlm.nih.gov/pubmed/32621646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.28140
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