Antithrombotic Effects of Combined PAR (Protease-Activated Receptor)-4 Antagonism and Factor Xa Inhibition

PAR (protease-activated receptor)-4 antagonism has antiplatelet effects under conditions of high shear stress. We aimed to establish whether PAR4 antagonism had additive antithrombotic activity in the presence of factor Xa inhibition in an ex vivo model of acute arterial injury. APPROACH AND RESULTS...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Arterioscler Thromb Vasc Biol
Päätekijät: Meah, Mohammed N., Raftis, Jennifer, Wilson, Simon J., Perera, Vidya, Garonzik, Samira M., Murthy, Bindu, Everlof, J. Gerry, Aronson, Ronald, Luettgen, Joseph, Newby, David E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Lippincott Williams & Wilkins 2020
Aiheet:
Translational Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7571844/
https://ncbi.nlm.nih.gov/pubmed/32907366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.120.314960
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