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Divergent Synthesis of Complex Diterpenes via a Hybrid Oxidative Approach

Polycyclic diterpenes exhibit many important biological activities, but de novo synthetic access to these molecules is highly challenging due to their structural complexity. Semisynthetic access has also been limited by the lack of chemical tools for scaffold modifications. We report a chemoenzymati...

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Dades bibliogràfiques
Publicat a:Science
Autors principals: Zhang, Xiao, King-Smith, Emma, Dong, Liao-Bin, Yang, Li-Cheng, Rudolf, Jeffrey D., Shen, Ben, Renata, Hans
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7569743/
https://ncbi.nlm.nih.gov/pubmed/32792393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abb8271
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