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Oncogenic mutant RAS signaling activity is rescaled by the ERK/MAPK pathway
Activating mutations in RAS are present in ~ 30% of human tumors, and the resulting aberrations in ERK/MAPK signaling play a central role in oncogenesis. However, the form of these signaling changes is uncertain, with activating RAS mutants linked to both increased and decreased ERK activation in vi...
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| Udgivet i: | Mol Syst Biol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7569415/ https://ncbi.nlm.nih.gov/pubmed/33073539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20209518 |
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