Patient-derived malignant pleural mesothelioma cell cultures: a tool to advance biomarker-driven treatments

Malignant pleural mesothelioma (MPM) is an aggressive cancer, associated with poor prognosis. We assessed the feasibility of patient-derived cell cultures to serve as an ex vivo model of MPM. Patient-derived MPM cell cultures (n=16) exhibited stemness features and reflected intratumour and interpati...

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Detalhes bibliográficos
Publicado no:Thorax
Main Authors: Kanellakis, Nikolaos I, Asciak, Rachelle, Hamid, Megat Abd, Yao, Xuan, McCole, Mark, McGowan, Simon, Seraia, Elena, Hatch, Stephanie, Hallifax, Rob J, Mercer, Rachel M, Bedawi, Eihab O, Jones, Stephanie, Verrill, Clare, Dobson, Melissa, George, Vineeth, Stathopoulos, Georgios T, Peng, Yanchun, Ebner, Daniel, Dong, Tao, Rahman, Najib M, Psallidas, Ioannis
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7569377/
https://ncbi.nlm.nih.gov/pubmed/32943495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2020-215027
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