Patient-derived malignant pleural mesothelioma cell cultures: a tool to advance biomarker-driven treatments

Malignant pleural mesothelioma (MPM) is an aggressive cancer, associated with poor prognosis. We assessed the feasibility of patient-derived cell cultures to serve as an ex vivo model of MPM. Patient-derived MPM cell cultures (n=16) exhibited stemness features and reflected intratumour and interpati...

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Bibliografische gegevens
Gepubliceerd in:Thorax
Hoofdauteurs: Kanellakis, Nikolaos I, Asciak, Rachelle, Hamid, Megat Abd, Yao, Xuan, McCole, Mark, McGowan, Simon, Seraia, Elena, Hatch, Stephanie, Hallifax, Rob J, Mercer, Rachel M, Bedawi, Eihab O, Jones, Stephanie, Verrill, Clare, Dobson, Melissa, George, Vineeth, Stathopoulos, Georgios T, Peng, Yanchun, Ebner, Daniel, Dong, Tao, Rahman, Najib M, Psallidas, Ioannis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMJ Publishing Group 2020
Onderwerpen:
Brief Communication
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7569377/
https://ncbi.nlm.nih.gov/pubmed/32943495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2020-215027
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