Patient-derived malignant pleural mesothelioma cell cultures: a tool to advance biomarker-driven treatments

Malignant pleural mesothelioma (MPM) is an aggressive cancer, associated with poor prognosis. We assessed the feasibility of patient-derived cell cultures to serve as an ex vivo model of MPM. Patient-derived MPM cell cultures (n=16) exhibited stemness features and reflected intratumour and interpati...

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Dettagli Bibliografici
Pubblicato in:Thorax
Autori principali: Kanellakis, Nikolaos I, Asciak, Rachelle, Hamid, Megat Abd, Yao, Xuan, McCole, Mark, McGowan, Simon, Seraia, Elena, Hatch, Stephanie, Hallifax, Rob J, Mercer, Rachel M, Bedawi, Eihab O, Jones, Stephanie, Verrill, Clare, Dobson, Melissa, George, Vineeth, Stathopoulos, Georgios T, Peng, Yanchun, Ebner, Daniel, Dong, Tao, Rahman, Najib M, Psallidas, Ioannis
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2020
Soggetti:
Brief Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7569377/
https://ncbi.nlm.nih.gov/pubmed/32943495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2020-215027
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