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Patient-derived malignant pleural mesothelioma cell cultures: a tool to advance biomarker-driven treatments

Malignant pleural mesothelioma (MPM) is an aggressive cancer, associated with poor prognosis. We assessed the feasibility of patient-derived cell cultures to serve as an ex vivo model of MPM. Patient-derived MPM cell cultures (n=16) exhibited stemness features and reflected intratumour and interpati...

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Dades bibliogràfiques
Publicat a:Thorax
Autors principals: Kanellakis, Nikolaos I, Asciak, Rachelle, Hamid, Megat Abd, Yao, Xuan, McCole, Mark, McGowan, Simon, Seraia, Elena, Hatch, Stephanie, Hallifax, Rob J, Mercer, Rachel M, Bedawi, Eihab O, Jones, Stephanie, Verrill, Clare, Dobson, Melissa, George, Vineeth, Stathopoulos, Georgios T, Peng, Yanchun, Ebner, Daniel, Dong, Tao, Rahman, Najib M, Psallidas, Ioannis
Format: Artigo
Idioma:Inglês
Publicat: BMJ Publishing Group 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7569377/
https://ncbi.nlm.nih.gov/pubmed/32943495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2020-215027
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