Biological effect of tissue plasminogen activator (t-PA) and DNase intrapleural delivery in pleural infection patients

BACKGROUND: Pleural infection (PI) is a major global disease with an increasing incidence, and pleural fluid (PF) drainage is essential for the successful treatment. The MIST2 study demonstrated that intrapleural administration of tissue plasminogen activator (t-PA) and DNase, or t-PA alone increase...

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Bibliographic Details
Published in:BMJ Open Respir Res
Main Authors: Kanellakis, Nikolaos I, Wrightson, John M, Hallifax, Rob, Bedawi, Eihab O, Mercer, Rachel, Hassan, Maged, Asciak, Rachelle, Hedley, Emma, Dobson, Melissa, Dong, Tao, Psallidas, Ioannis, Rahman, Najib M
Format: Artigo
Language:Inglês
Published: BMJ Publishing Group 2019
Subjects:
Pleural Disease
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6797395/
https://ncbi.nlm.nih.gov/pubmed/31673364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjresp-2019-000440
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