SARS-CoV-2 Is Restricted by Zinc Finger Antiviral Protein despite Preadaptation to the Low-CpG Environment in Humans

Recent evidence shows that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is sensitive to interferons (IFNs). However, the most effective types of IFNs and the underlying antiviral effectors remain to be defined. Here, we show that zinc finger antiviral protein (ZAP), which preferentia...

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Bibliografiske detaljer
Udgivet i:mBio
Main Authors: Nchioua, Rayhane, Kmiec, Dorota, Müller, Janis A., Conzelmann, Carina, Groß, Rüdiger, Swanson, Chad M., Neil, Stuart J. D., Stenger, Steffen, Sauter, Daniel, Münch, Jan, Sparrer, Konstantin M. J., Kirchhoff, Frank
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7569149/
https://ncbi.nlm.nih.gov/pubmed/33067384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01930-20
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